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The airstrikes on the southern outskirts of the Lebanese capital, an area where Hezbollah holds sway, were some of the heaviest since a U.S.-brokered cease-fire came into effect in November.
Ayatollah Ali Khamenei said that abandoning uranium enrichment would be against Iran’s interests.
Israel said the bombing of the airport, which was targeted for the second time this month, had destroyed the last plane used by the Iran-backed Houthi militia.
After war with Israel weakened Iran-backed militias across the Middle East, including the Lebanese group Hezbollah, Lebanon’s government has moved to assert its authority over armed groups.
Iranian officials said their foreign minister had proposed a joint nuclear-enrichment venture, involving Arab countries and American investment.
On Sunday, a Houthi ballistic missile evaded Israel’s multilayered aerial defenses and landed near Ben-Gurion International Airport.
There was no immediate comment from the American military about the joint operation, the first since President Trump took office.
The death toll from the explosion rose to 70, as officials said the massive blast involved a shipment whose documentation obscured the nature of the substances it carried.
Officials said Iran and the U.S. made some progress during the latest round of talks in Rome on Friday.
In an interview with The New York Times, President Ahmed al-Shara urged the United States to lift sanctions and alluded to the possibility of future military support from Russia and Turkey.