The Defense Advanced Research Projects Agency (DARPA) is hosting an in-person gathering in San Francisco Feb. 21-22 to engage with science and technology companies, universities, and other research and engineering organizations interested in exploring scientific areas ripe for disruption. The event, called Discover DSO Day (D3), is sponsored by DARPA’s Defense Sciences Office (DSO), whose goal is to identify and pursue high-risk, high-payoff research initiatives across a broad spectrum of science and engineering disciplines and transform them into important, new game-changing technologies for U.S. national security.